Endocrine Abstracts

Introduction: Cushing’s disease (CD) is reported in 60-70% of all patients with Cushing’s syndrome (CS), but occurs only in approximately 33% of the reported CS cases in pregnancy. Nevertheless, despite its rarity, pregnancy in patients with CS can be troublesome because of the risk of maternal-fetal complications.Observation: A 28-year-old female patient was referred to our endocrinology department for a suspected CS with morphological alter...

Introduction: Leydig cell tumors (LCTs) are uncommon neoplasms arising from gonadal stroma, accounting for 1–3% of all testicular tumors in adults. The etiology of LCT remains unclear. About 25% of LCTs secrete predominantly estrogens, which produce gynecomastia.Observation: We report a case of a 53-year-old male patient who sought evaluation for bilateral gynecomastia. He had a long-term use of amitriptyline and benzodiazepine. The physical examin...

Introduction: Medullary thyroid carcinoma (MTC) represents 3–10% of all thyroid cancer. The presence of papillary thyroid microcarcinoma (mPTC) in patients undergoing thyroidectomy for multinodular goiter has been reported as 3–7%.The occurrence of multiple thyroid cancers of different origin in one individual patient is a rare event. We report the case of synchronous papillary and medullary thyroid cancer developed in heterogynous recurrent ...

IntroductionAcid sphingomyelinase-deficient Niemann–Pick disease (NPD) is a lysosomal lipid storage disorder. We report a new case of Hashimoto thyroiditis associated to primary adrenal insufficiency (PAI) likely of infiltrative process occurring in NPD type B patient.ObservationA 24-year-old Tunisian female patient was followed up in our endocrinology department for Hashimoto thyroiditis. Two years late...

IntroductionGrave’s disease is an autoimmune thyroid disorder. It is the most frequent cause of hyperthyroidism with variable manifestations. When not recognized in time and not adequately treated, Graves’ disease poses serious risks and can have severe complications.ObservationA 63-year-old female was admitted to the endocrinology department for severe thyrotoxicosis. She was diagnosed in 2011 with...

IntroductionParagangliomas (PGs) are rare tumors arising from sympathetic and parasympathetic paraganglia with an incidence of 15–20%. We report a case of a pre-operative diagnosis of retroperitoneal PGs evoked on anatomic imaging confirmed by biochemical evaluation.ObservationA 55-year-old female was referred to the endocrinology department for investigation of a paroxistic hypertension. For her persona...